In the introduction to the essay “Fueling the Imagination” from her book, Hiking the Horizontal, Liz Lerman recounts a conversation with Nobel laureate and scientist, Dr. Eric Wieschaus about how he asks himself a question. “I am fueled by my own ignorance,” he says with keen precision. Artists and scientists share an understanding, Lerman writes, “that not knowing is fuel for the imagination rather than fuel for humiliation.” This cross disciplinary discussion from the 2016 conference explored our relationship with not knowing and how we engage with work, questions and conversation to generate creativity.